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Imuran Azamune 50mg (Azathioprine, Imuran) Manufactured by Leiras |
100 tablets 50mg
Price: $100
Used with other drugs
to prevent rejection of kidney transplants. It also is used to treat severe
rheumatoid arthritis.
In the U.S.—
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In Canada—
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Category
Imuran belongs to the
group of medicines known as immunosuppressive agents. It is used to reduce the
body's natural immunity in patients who receive organ transplants. It is also
used to treat rheumatoid arthritis. Imuran
may also be used for other conditions as determined by your doctor.
Imuran is a very
strong medicine. You and your doctor should talk about the need for this
medicine and its risks. Even though Imuran
may cause side effects that could be very serious, remember that it may be
required to treat your medical problem.
Imuran is available
only with your doctor's prescription, in the following dosage forms:
Oral
Parenteral
In deciding to use a medicine, the risks of taking the
medicine must be weighed against the good it will do. This is a decision you and
your doctor will make. For Imuran, the
following should be considered:
Allergies—Tell
your doctor if you have ever had any unusual or allergic reaction to
Imuran. Also tell your health care professional
if you are allergic to any other substances, such as foods, preservatives, or
dyes.
Pregnancy—Use
of Imuran is not recommended during
pregnancy. It may cause birth defects if either the male or the female is using
it at the time of conception. The use of birth control methods is recommended.
If you have any questions about this, check with your doctor.
Breast-feeding—Imuran
passes into breast milk. Because this medicine may cause serious side effects,
breast-feeding is generally not recommended while you are using it.
Children—This
medicine has been tested in children and, in effective doses, has not been shown
to cause different side effects or problems than it does in adults.
Older adults—Many
medicines have not been studied specifically in older people. Therefore, it may
not be known whether they work exactly the same way they do in younger adults.
Although there is no specific information comparing use of
Imuran in the elderly with use in other age
groups, this medicine is not expected to cause different side effects or
problems in older people than it does in younger adults.
The effects of Imuran
may cause increased infections and delayed healing. Dental work, whenever
possible, should be completed prior to beginning this medicine.
Other medicines—Although
certain medicines should not be used together at all, in other cases two
different medicines may be used together even if an interaction might occur. In
these cases, your doctor may want to change the dose, or other precautions may
be necessary. When you are taking or receiving Imuran
it is especially important that your health care professional know if you are
taking any of the following:
Other medical problems—The
presence of other medical problems may affect the use of
Imuran. Make sure you tell your doctor if you
have any other medical problems, especially:
Use this medicine only as directed by your doctor
This medicine is sometimes given together with certain
other medicines. If you are using a combination of medicines, make sure that you
take each one at the proper time and do not mix them up. Ask your health care
professional to help you plan a way to remember to take your medicines at the
right times.
Do not stop taking this medicine without first checking
with your doctor
Imuran sometimes
causes nausea or vomiting. Taking this medicine after meals or at bedtime may
lessen stomach upset. Ask your health care professional for other ways to lessen
these effects.
If you vomit shortly after taking a dose of
Imuran, check with your doctor. You will be
told whether to take the dose again or to wait until the next scheduled dose.
The dose of Imuran
will be different for different patients. Follow your doctor's orders or the
directions on the label. The following information includes only the average
doses of Imuran. If your dose is
different, do not change it unless your doctor tells you to do so.
The number of doses you take each day, the time allowed
between doses, and the length of time you take the medicine depend on the
medical problem for which you are taking Imuran
If you miss a dose of this medicine and your dosing
schedule is:
To store this medicine:
It is very important that your doctor check your
progress at regular visits
While you are being treated with
Imuran, and after you stop treatment with it, it is important to
see your doctor about the immunizations (vaccinations) you should receive. Do
not get any immunizations without your doctor's approval.
Imuran lowers your body's resistance to
infections. For some immunizations, there is a chance you might get the
infection the immunization is meant to prevent. For other immunizations, it may
be especially important to receive the immunization to prevent a disease. In
addition, other persons living in your household should not take oral polio
vaccine since there is a chance they could pass the polio virus on to you. Also,
avoid persons who have recently taken oral polio vaccine. Do not get close to
them, and do not stay in the same room with them for very long. If you cannot
take these precautions, you should consider wearing a protective face mask that
covers the nose and mouth.
Imuran can temporarily
lower the number of white blood cells in your blood, increasing the chance of
getting an infection. It can also lower the number of platelets, which are
necessary for proper blood clotting. If this occurs, there are certain
precautions you can take, especially when your blood count is low, to reduce the
risk of infection or bleeding:
Along with its needed effects, a medicine may cause some
unwanted effects. Some side effects will have signs or symptoms that you can see
or feel. Your doctor will watch for others by doing certain tests.
Also, because of the way this medicine acts on the body,
there is a chance that it might cause other unwanted effects that may not occur
until months or years after the medicine is used. These delayed effects may
include certain types of cancer, such as leukemia, lymphoma, or skin cancer.
However, the risk of cancer seems to be lower in people taking
Imuran for arthritis. Discuss these possible
effects with your doctor.
Check with your doctor as soon as possible if any of the
following side effects occur:
More common
Cough or hoarseness; fever or
chills ; lower back or side pain; painful or difficult urination; unusual
tiredness or weakness
Less common
Black, tarry stools; blood in
urine or stools; pinpoint red spots on skin; unusual bleeding or bruising
Rare
Fast heartbeat; fever (sudden);
muscle or joint pain; nausea, vomiting, and diarrhea (severe); redness or
blisters on skin ; shortness of breath; sores in mouth and on lips; stomach
pain; swelling of feet or lower legs; unusual feeling of discomfort or illness
(sudden)
This medicine may also cause the following side effect
that your doctor will watch for:
Less common
Liver problems
For patients taking this medicine for rheumatoid
arthritis:
·
Signs and symptoms of blood problems (black, tarry stools; blood in urine or
stools; cough or hoarseness; fever or chills; lower back or side pain; painful
or difficult urination; pinpoint red spots on skin; unusual tiredness or
weakness; or unusual bleeding or bruising) are less likely to occur in patients
taking Imuran for rheumatoid arthritis than
in patients taking Imuran for transplant
rejection. This is because lower doses are often used.
Other side effects may occur that usually do not need
medical attention. These side effects may go away during treatment as your body
adjusts to the medicine. However, check with your doctor if any of the following
side effects continue or are bothersome:
More common
Loss of appetite; nausea or
vomiting
Less common
Skin rash
After you stop using this medicine, it may still produce
some side effects that need attention. During this period of time check with
your doctor as soon as possible if you notice any of the following:
Black, tarry stools; blood in
urine ; cough or hoarseness; fever or chills; lower back or side pain;
painful or difficult urination; pinpoint red spots on skin; unusual bleeding
or bruising
Other side effects not listed above may also occur in some
patients. If you notice any other effects, check with your doctor.
Once a medicine has been approved for marketing for a
certain use, experience may show that it is also useful for other medical
problems. Although these uses are not included in product labeling,
Imuran is used in certain patients with the
following medical conditions:
Other than the above information, there is no additional
information relating to proper use, precautions, or side effects for these uses
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